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to drink fluids liberally along with doxycycline to reduce the risk of esophageal irritation and ulceration see Adverse Reactions 6. <a href=https://buydoxycyclineon.com/>can doxycycline treat bv</a> The main mediators of a reaction are biogenic amines histamine, serotonin, catecholamines, vasoactive polypeptides kinins, cationic proteins, complement system anaphylaxins C 3A, C 5A, C 567, lysosomal enzymes, vasoactive lipids prostaglandins, endoperoxides, thromboxanes, phospholipids platelet activating factor and chemotactic substances 5, 6.